This symposium explores cutting-edge applications of artificial intelligence (AI) and technology in primary care settings, focusing on innovative studies conducted in Singapore primary care. The studies showcase the practical applications of AI and technology in addressing key challenges in primary care: patient safety and clinical decision support. The symposium will discuss the implications of these innovations, including their potential to improve care quality, enhance efficiency, and support healthcare professionals in their daily practice. Additionally, it will explore the limitations of current research and future directions for implementation, scalability, and long-term impact assessment of these technologies in primary care settings.